During 1â3 July 2024 we assessed the detection of the NSW H7N8 HPAI virus by twelve diagnostic assays used by NSW Health Pathology (NSWHP) laboratories. We subsequently also reviewed the 12â25 November 2024 data from the Royal College of Pathologists of Australasia Quality Assurance Programs (RCPAQAP) Emerging Biological Threats survey, assessing the detection of five other avian influenza viruses: H5N1, H7N3, H7N9, H9N2, and H10N7. These assessments were needed because knowledge of the ability to detect avian influenza virus on human diagnostic platforms is critical for minimising public anxiety in the event of human infections, and facilitates public health response planning.